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KMID : 0369819830130010044
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Jorunal of Korean Pharmaceutical Sciences
1983 Volume.13 No. 1 p.44 ~ p.44
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The 12th Annual Academic Convention ; Determination of Prednisolone in Tablets by High Performance Liquid Chromatography
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김형국/Kim HK
고건일/김재백/Ko GI/Kim JB
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Abstract
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A convenient high performance liquid chromatographic method for the quantitative determination and content uniformity of prednisolone in tablets is described. The prednisolone was chromatographed using a μ?BondapakC18 column and the eluent 70% MeOH at a flow rate 1. 0ml/min. Diethylstilbestrol was used as an internal standard. The UV detector response at 254nm was linear over a range of 10∼60μg/ml under conditions of the analysis. Reproducibility studies gave relative standard deviations of 0.3∼0.5.
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